RADIOLABELLED DERIVATIVES OF A 2-AMINO-6-FLUORO-N-[5-FLUORO-PYRIDIN-3-YL]- PYRAZOLO[1,5-A]PYRIMIDIN-3-CARBOXAMIDE COMPOUND USEFUL AS ATR KINASE INHIBITOR, THE PREPARATION OF SAID COMPOUND AND DIFFERENT SOLID FORMS THEREOF
The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this inventio...
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Zusammenfassung: | The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and solid forms of the compounds of this invention. The compounds of this invention have formula (I-l) or (I-A); wherein the variables are as defined herein.
L'invention concerne des composés utiles en tant qu'inhibiteurs de la protéine kinase ATR. L'invention concerne également des compositions pharmaceutiquement acceptables comprenant les composés de l'invention; des méthodes de traitement de diverses maladies, de divers troubles et états à l'aide des composés de l'invention; des procédés de préparation de ces composés; des intermédiaires pour la préparation des composés de l'invention; et des formes solides de ces composés Les composés de cette invention ont la formule (I-I) ou (I-A), les variables étant telles que définies présentement. |
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