SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS

SYNTHESIS OF POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS

Intermediates in the synthetic pathway of polycyclic carbamoylpyridone compounds useful for the treatment of HIV are disclosed. Methods of manufacture of the intermediates are also disclosed. For example, compounds of Formula C-1 and B-10.-1 and methods of manufacture thereof are described, as shown...

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Bibliographische Detailangaben
Hauptverfasser: IKEMOTO, NORIHIRO, GRIGGS, NOLAN, KEATON, KATIE ANN, HERPT, JO VAN, LEEMAN, MICHEL, SCHRIER, KATE, TRINIDAD, JONATHAN, CHIU, ANNA, HALE, CHRISTOPHER, KRAFT, MATT, ENQUIST, JOHN, PENG, ZHIHUI, LAZERWITH, SCOTT E, WALTMAN, ANDREW W
Format: Patent
Sprache:eng ; fre
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Intermediates in the synthetic pathway of polycyclic carbamoylpyridone compounds useful for the treatment of HIV are disclosed. Methods of manufacture of the intermediates are also disclosed. For example, compounds of Formula C-1 and B-10.-1 and methods of manufacture thereof are described, as shown in the schemes below. (see above formula) L'invention concerne des procédés de fabrication des composés de formule (I).