ANTIMICROBIAL COMPOSITIONS

Storage-stable compositions for generating antimicrobial activity are described. The compositions comprise an enzyme that is able to convert a substrate to release hydrogen peroxide, and an unrefined natural substance, such as a honey, that includes a substrate for the enzyme. In certain embodiments...

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Bibliographische Detailangaben
Hauptverfasser:	BARRETT, JOHN REGINALD, STAPLES, IAN, PATTON, THOMAS, BRENNAN, JAMES
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMICAL RIPENING OF FRUIT OR VEGETABLES DISINFECTION, STERILISATION, OR DEODORISATION OF AIR FISHING FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J FORESTRY HUMAN NECESSITIES HUNTING HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL PRESERVING, e.g. BY CANNING, MEAT, FISH, EGGS, FRUIT,VEGETABLES, EDIBLE SEEDS THE PRESERVED, RIPENED, OR CANNED PRODUCTS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES TRAPPING
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Beschreibung
Zusammenfassung:	Storage-stable compositions for generating antimicrobial activity are described. The compositions comprise an enzyme that is able to convert a substrate to release hydrogen peroxide, and an unrefined natural substance, such as a honey, that includes a substrate for the enzyme. In certain embodiments, the enzyme is a purified enzyme. In other embodiments, the substrate lacks catalase activity, and the enzyme is additional to any enzyme activity able to convert the substrate to release hydrogen peroxide that may be present in the unrefined natural substance. The storage-stable compositions do not include sufficient free water to allow the enzyme to convert the substrate. Use of the compositions to treat microbial infections and wounds is described, as well as methods for their production. L'invention concerne des compositions stables au stockage pour générer une activité antimicrobienne. Les compositions comprennent une enzyme qui peut convertir un substrat pour libérer du peroxyde d'hydrogène, et une substance naturelle non raffinée, telle que du miel, qui comprend un substrat pour l'enzyme. Dans certains modes de réalisation, l'enzyme est une enzyme purifiée. Dans d'autres modes de réalisation, le substrat est dépourvu d'activité catalase, et l'enzyme est complémentaire à toute activité enzymatique pouvant convertir le substrat pour libérer du peroxyde d'hydrogène qui peut être présent dans la substance naturelle non raffinée. Les compositions stables au stockage ne comprennent pas d'eau libre suffisante pour permettre à l'enzyme de convertir le substrat. L'invention concerne l'utilisation des compositions pour traiter des infections microbiennes et des plaies, ainsi que des procédés pour leur production.