SPIRO UREA COMPOUNDS AS RSV ANTIVIRAL COMPOUNDS

The invention concerns novel substituted spiro urea azetidinyl or piperidinyl compounds of formula (I) having antiviral activity, in particular, having an inhibitory activity on the replication of the respiratory syncytial virus (RSV). The invention further concerns the preparation of such novel com...

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Bibliographische Detailangaben
Hauptverfasser:	HU, LILI, DEMIN, SAMUEL DOMINIQUE, RABOISSON, PIERRE JEAN-MARIE BERNARD, TAHRI, ABDELLAH, VENDEVILLE, SANDRINE MARIE HELENE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention concerns novel substituted spiro urea azetidinyl or piperidinyl compounds of formula (I) having antiviral activity, in particular, having an inhibitory activity on the replication of the respiratory syncytial virus (RSV). The invention further concerns the preparation of such novel compounds, compositions comprising these compounds, and the compounds for use in the treatment of respiratory syncytial virus infection. La présente invention concerne de nouveaux composés spiro d'urée azétidinyle ou pipéridinyle substitués de formule (I) possédant une activité antivirale, en particulier possédant une activité inhibitrice sur la réplication du virus respiratoire syncytial (VRS). L'invention concerne en outre la préparation de ces nouveaux composés, des compositions contenant ces composés, et lesdits composés destinés à être utilisés pour traiter une infection due au virus respiratoire syncytial.