AZASPIRO DERIVATIVES AS TRPM8 ANTAGONISTS

The present invention relates to azaspiro derivatives of the formula (I) or a pharmaceutically acceptable salt thereof or a prodrug thereof, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders which are mediated via the TRP...

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Bibliographische Detailangaben
Hauptverfasser:	OHMI, MASASHI, ANDO, KAZUO, SHISHIDO, YUJI
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to azaspiro derivatives of the formula (I) or a pharmaceutically acceptable salt thereof or a prodrug thereof, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders which are mediated via the TRPM8 receptor. La présente invention concerne des dérivés azaspiro de formule (I) ou un sel pharmaceutiquement acceptable de ceux-ci, ou un promédicament de ceux-ci, leurs procédés de préparation, des compositions pharmaceutiques les contenant et leur utilisation dans le traitement de divers troubles médiés par le récepteur TRMP8.