NEW SOLVATED CRYSTAL FORM OF RIFAXIMIN, PRODUCTION, COMPOSITIONS AND USES THEREOF

ABSTRACT Disclosed is a new crystalline form of rifaximin, that it is a solvated form of rifaximin called rifaximin r. Also disclosed is a process for the preparation of rifaximin r, a pharmaceutical composition comprising said rifaximin form, and its use to treat inflammations and infections. Date...

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Bibliographische Detailangaben
Hauptverfasser:	MAFFEI, PAOLA, GREPIONI, FABRIZIA, SFORZINI, ANNALISA, VISCOMI, GIUSEPPE CLAUDIO, CHELAZZI, LAURA
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	ABSTRACT Disclosed is a new crystalline form of rifaximin, that it is a solvated form of rifaximin called rifaximin r. Also disclosed is a process for the preparation of rifaximin r, a pharmaceutical composition comprising said rifaximin form, and its use to treat inflammations and infections. Date Recue/Date Received 2021-03-12 L'invention concerne une nouvelle forme cristalline de la rifaximine, caractérisée en ce qu'il s'agit d'une forme solvatée d'éther monoéthylique de diéthylène glycol de la rifaximine appelée rifaximine t (Tau). Un procédé de préparation de rifaximine t, une composition pharmaceutique contenant ladite forme de rifaximine, et son utilisation pour traiter des inflammations et des infections sont en outre décrits.