THERAPEUTIC NANOPARTICLES COMPRISING A THERAPEUTIC AGENT AND METHODS OF MAKING AND USING SAME

The present disclosure generally relates to nanoparticles comprising a substantially hydrophobic acid, a basic therapeutic agent having a protonatable nitrogen, and a polymer. Other aspects include methods of making and using such nanoparticles. La présente invention porte d'une manière général...

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Hauptverfasser: WANG, HONG, DEWITT, DAVID, SONG, YOUNG-HO, FIGUEIREDO, MARIA, TROIANO, GREG, PEEKE, ERICK, VAN GEEN HOVEN, CHRISTINA, WRIGHT, JAMES
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creator WANG, HONG
DEWITT, DAVID
SONG, YOUNG-HO
FIGUEIREDO, MARIA
TROIANO, GREG
PEEKE, ERICK
VAN GEEN HOVEN, CHRISTINA
WRIGHT, JAMES
description The present disclosure generally relates to nanoparticles comprising a substantially hydrophobic acid, a basic therapeutic agent having a protonatable nitrogen, and a polymer. Other aspects include methods of making and using such nanoparticles. La présente invention porte d'une manière générale sur des nanoparticules comprenant un acide essentiellement hydrophobe, un agent thérapeutique basique possédant un azote protonable, et un polymère. D'autres aspects concernent des procédés de fabrication et d'utilisation de telles nanoparticules.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title THERAPEUTIC NANOPARTICLES COMPRISING A THERAPEUTIC AGENT AND METHODS OF MAKING AND USING SAME
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