DIAGNOSTIC REAGENTS FOR IMPROVED IN VIVO OR IN VITRO CELL-MEDIATED IMMUNOLOGICAL DIAGNOSIS OF TUBERCULOSIS

The present invention discloses in vitro and in vivo diagnostic methods with enhanced specificity and sensitivity for the detection of tuberculosis. The diagnostic re agents of the present invention can replace former mixtures/cocktails/pools of antigens comprising ESAT-6 but including ESAT6 improve...

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Bibliographische Detailangaben
Hauptverfasser:	HOFF, SOREN TETENS, AGGER, ELSE MARIE, ANDERSEN, PETER LAWAETZ, AAGAARD, CLAUS, ROSENKRANDS, ISA
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING
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Beschreibung
Zusammenfassung:	The present invention discloses in vitro and in vivo diagnostic methods with enhanced specificity and sensitivity for the detection of tuberculosis. The diagnostic re agents of the present invention can replace former mixtures/cocktails/pools of antigens comprising ESAT-6 but including ESAT6 improves the diagnosis even further. La présente invention concerne des méthodes diagnostiques in vitro et in vivo présentant une spécificité et une sensibilité améliorées pour la détection de la tuberculose. Les réactifs de diagnostic de la présente invention peuvent remplacer les anciens mélanges/cocktails/groupes d'antigènes comprenant l'ESAT-6, l'ESAT6 améliorant encore davantage le diagnostic.