NMDA ANTAGONIST PRODRUGS
Prodrugs of an NMDA antagonist, (S)-1-phenyl-2-(pyridin-2-yl)ethanamine, which may be used in the treatment of depression or pain are provided, such as compounds of formula (I) (see formula I) (see formula above) wherein R1 is C1-6 alkylC(O)O(C1-6 alkoxy) or , and wherein AA is a peptide bond-linked...
Gespeichert in:
| Hauptverfasser: | , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | NORDVALL, GUNNAR QUIRK, MICHAEL BERNSTEIN, PETER ROBERT MALMBORG, PER JONAS WEIGELT, DIRK REINHOLD HOGDIN, KATHARINA BALESTRA, MICHAEL KERS, ANNIKA |
| description | Prodrugs of an NMDA antagonist, (S)-1-phenyl-2-(pyridin-2-yl)ethanamine, which may be used in the treatment of depression or pain are provided, such as compounds of formula (I) (see formula I) (see formula above) wherein R1 is C1-6 alkylC(O)O(C1-6 alkoxy) or , and wherein AA is a peptide bond-linked natural amino acid; or a pharmaceutically acceptable salt thereof.
Promédicaments d'un antagoniste de NMDA, (S) -1-phényl -2-(pyridin-2-yl) éthanamine, utiles pour le traitement de la dépression (en particulier un trouble dépressif majeur) ou de la douleur; compositions les comprenant; et procédés de fabrication de ceux-ci. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CA2928004C</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CA2928004C</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CA2928004C3</originalsourceid><addsrcrecordid>eNrjZJDw83VxVHD0C3F09_fzDA5RCAjydwkKdQ_mYWBNS8wpTuWF0twM8m6uIc4euqkF-fGpxQWJyal5qSXxzo5GlkYWBgYmzsaEVQAAgT8e5Q</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>NMDA ANTAGONIST PRODRUGS</title><source>esp@cenet</source><creator>NORDVALL, GUNNAR ; QUIRK, MICHAEL ; BERNSTEIN, PETER ROBERT ; MALMBORG, PER JONAS ; WEIGELT, DIRK REINHOLD ; HOGDIN, KATHARINA ; BALESTRA, MICHAEL ; KERS, ANNIKA</creator><creatorcontrib>NORDVALL, GUNNAR ; QUIRK, MICHAEL ; BERNSTEIN, PETER ROBERT ; MALMBORG, PER JONAS ; WEIGELT, DIRK REINHOLD ; HOGDIN, KATHARINA ; BALESTRA, MICHAEL ; KERS, ANNIKA</creatorcontrib><description>Prodrugs of an NMDA antagonist, (S)-1-phenyl-2-(pyridin-2-yl)ethanamine, which may be used in the treatment of depression or pain are provided, such as compounds of formula (I) (see formula I) (see formula above) wherein R1 is C1-6 alkylC(O)O(C1-6 alkoxy) or , and wherein AA is a peptide bond-linked natural amino acid; or a pharmaceutically acceptable salt thereof.
Promédicaments d'un antagoniste de NMDA, (S) -1-phényl -2-(pyridin-2-yl) éthanamine, utiles pour le traitement de la dépression (en particulier un trouble dépressif majeur) ou de la douleur; compositions les comprenant; et procédés de fabrication de ceux-ci.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220412&DB=EPODOC&CC=CA&NR=2928004C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220412&DB=EPODOC&CC=CA&NR=2928004C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>NORDVALL, GUNNAR</creatorcontrib><creatorcontrib>QUIRK, MICHAEL</creatorcontrib><creatorcontrib>BERNSTEIN, PETER ROBERT</creatorcontrib><creatorcontrib>MALMBORG, PER JONAS</creatorcontrib><creatorcontrib>WEIGELT, DIRK REINHOLD</creatorcontrib><creatorcontrib>HOGDIN, KATHARINA</creatorcontrib><creatorcontrib>BALESTRA, MICHAEL</creatorcontrib><creatorcontrib>KERS, ANNIKA</creatorcontrib><title>NMDA ANTAGONIST PRODRUGS</title><description>Prodrugs of an NMDA antagonist, (S)-1-phenyl-2-(pyridin-2-yl)ethanamine, which may be used in the treatment of depression or pain are provided, such as compounds of formula (I) (see formula I) (see formula above) wherein R1 is C1-6 alkylC(O)O(C1-6 alkoxy) or , and wherein AA is a peptide bond-linked natural amino acid; or a pharmaceutically acceptable salt thereof.
Promédicaments d'un antagoniste de NMDA, (S) -1-phényl -2-(pyridin-2-yl) éthanamine, utiles pour le traitement de la dépression (en particulier un trouble dépressif majeur) ou de la douleur; compositions les comprenant; et procédés de fabrication de ceux-ci.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJDw83VxVHD0C3F09_fzDA5RCAjydwkKdQ_mYWBNS8wpTuWF0twM8m6uIc4euqkF-fGpxQWJyal5qSXxzo5GlkYWBgYmzsaEVQAAgT8e5Q</recordid><startdate>20220412</startdate><enddate>20220412</enddate><creator>NORDVALL, GUNNAR</creator><creator>QUIRK, MICHAEL</creator><creator>BERNSTEIN, PETER ROBERT</creator><creator>MALMBORG, PER JONAS</creator><creator>WEIGELT, DIRK REINHOLD</creator><creator>HOGDIN, KATHARINA</creator><creator>BALESTRA, MICHAEL</creator><creator>KERS, ANNIKA</creator><scope>EVB</scope></search><sort><creationdate>20220412</creationdate><title>NMDA ANTAGONIST PRODRUGS</title><author>NORDVALL, GUNNAR ; QUIRK, MICHAEL ; BERNSTEIN, PETER ROBERT ; MALMBORG, PER JONAS ; WEIGELT, DIRK REINHOLD ; HOGDIN, KATHARINA ; BALESTRA, MICHAEL ; KERS, ANNIKA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2928004C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2022</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>NORDVALL, GUNNAR</creatorcontrib><creatorcontrib>QUIRK, MICHAEL</creatorcontrib><creatorcontrib>BERNSTEIN, PETER ROBERT</creatorcontrib><creatorcontrib>MALMBORG, PER JONAS</creatorcontrib><creatorcontrib>WEIGELT, DIRK REINHOLD</creatorcontrib><creatorcontrib>HOGDIN, KATHARINA</creatorcontrib><creatorcontrib>BALESTRA, MICHAEL</creatorcontrib><creatorcontrib>KERS, ANNIKA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>NORDVALL, GUNNAR</au><au>QUIRK, MICHAEL</au><au>BERNSTEIN, PETER ROBERT</au><au>MALMBORG, PER JONAS</au><au>WEIGELT, DIRK REINHOLD</au><au>HOGDIN, KATHARINA</au><au>BALESTRA, MICHAEL</au><au>KERS, ANNIKA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>NMDA ANTAGONIST PRODRUGS</title><date>2022-04-12</date><risdate>2022</risdate><abstract>Prodrugs of an NMDA antagonist, (S)-1-phenyl-2-(pyridin-2-yl)ethanamine, which may be used in the treatment of depression or pain are provided, such as compounds of formula (I) (see formula I) (see formula above) wherein R1 is C1-6 alkylC(O)O(C1-6 alkoxy) or , and wherein AA is a peptide bond-linked natural amino acid; or a pharmaceutically acceptable salt thereof.
Promédicaments d'un antagoniste de NMDA, (S) -1-phényl -2-(pyridin-2-yl) éthanamine, utiles pour le traitement de la dépression (en particulier un trouble dépressif majeur) ou de la douleur; compositions les comprenant; et procédés de fabrication de ceux-ci.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre |
| recordid | cdi_epo_espacenet_CA2928004C |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | NMDA ANTAGONIST PRODRUGS |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-12T13%3A03%3A34IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=NORDVALL,%20GUNNAR&rft.date=2022-04-12&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECA2928004C%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |