CARBOXAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B

Inhibitors of HBV replication of formula (I) including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein X, R1 to R7 have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing...

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Bibliographische Detailangaben
Hauptverfasser:	KESTELEYN, BART RUDOLF ROMANIE, RABOISSON, PIERRE JEAN-MARIE BERNARD, VANDYCK, KOEN, HACHE, GEERWIN YVONNE PAUL
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Inhibitors of HBV replication of formula (I) including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein X, R1 to R7 have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy. L'invention concerne des inhibiteurs de la réplication du VHB de formule (I), y compris des formes stéréochimiquement isomères, et des sels, hydrates et solvates de ceux-ci, X et R1 à R7 ayant la signification donnée dans la description. La présente invention concerne également des procédés de préparation desdits composés, des compositions pharmaceutiques les contenant et leur utilisation, seuls ou en combinaison avec d'autres inhibiteurs du VHB, pour le traitement du VHB.