CELL-SEEDED COMPOSITIONS AND METHODS USEFUL FOR TREATING BONE REGIONS

Compositions and methods for treating diseased or damaged bone, preferably ischemic and/or necrotic bone, include the use of a combination of endothelial progenitor cells and mesenchymal stem cells, desirably also in conjunction with a collagenous extracellular matrix tissue. Methods for preparation...

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Bibliographische Detailangaben
Hauptverfasser:	TAYLOR, AMANDA F, STEINHART, CHRISTINE M, FEARNOT, NEAL E, WALLACE, SHELLEY L, CHARLEBOIS, STEVEN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:	Compositions and methods for treating diseased or damaged bone, preferably ischemic and/or necrotic bone, include the use of a combination of endothelial progenitor cells and mesenchymal stem cells, desirably also in conjunction with a collagenous extracellular matrix tissue. Methods for preparation of such compositions are also described. L'invention concerne des compositions et des procédés de traitement d'os malade ou lésé, de préférence un os ischémique et/ou nécrotique, qui comprennent l'utilisation d'une combinaison de cellules progénitrices endothéliales et de cellules souches mésenchymateuses, de préférence également en combinaison avec un tissu matriciel extracellulaire collagène. L'invention concerne également des procédés de préparation de ces compositions.