HETEROBICYCLOARYL RORC2 INHIBITORS AND METHODS OF USE THEREOF

The present invention provides compounds, pharmaceutical compositions, methods of inhibiting RORy activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such compounds and pharmaceutical compositions. La présente invention concerne des comp...

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Bibliographische Detailangaben
Hauptverfasser:	WENNERSTAL, GORAN MATTIAS, JONES, PETER, THORARENSEN, ATLI, KIEFER, JAMES RICHARD, JR, ZAPF, CHRISTOPH WOLFGANG, MEYERS, MARVIN JAY, MENTE, SCOT RICHARD, SCHNUTE, MARK EDWARD, BLINN, JAMES ROBERT, FLICK, ANDREW CHRISTOPHER, XING, LI, KURUMBAIL, RAVI G, ZAMARATSKI, EDOUARD, KAILA, NEELU
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides compounds, pharmaceutical compositions, methods of inhibiting RORy activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such compounds and pharmaceutical compositions. La présente invention concerne des composés, des compositions pharmaceutiques, des méthodes d'inhibition de l'activité de ROR? et/ou de réduction de la quantité d'IL-17 chez un sujet, ainsi que des méthodes de traitement de différents troubles médicaux à l'aide desdits composés et desdites compositions pharmaceutiques.