TRICYCLIC PYRROLE COMPOUNDS, THEIR PREPARATION AND USE IN MEDICAMENTS

The invention refers to compounds of general formula (I) wherein the variables take the various meanings, pharmaceutical compositions containing them and their use in medicine: The compounds have shown to be useful in therapy as angiogenesis inhibitors. The compounds are isolated from the fermentati...

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Bibliographische Detailangaben
Hauptverfasser:	CALVO PELAZ, BELINDA, MEDINA TORRES, MIGUEL ANGEL, MARTINEZ INSUA, MARTA, SANCHEZ LOPEZ, JOSE MARIA, RODRIGUEZ QUESADA, ANA, FERNANDEZ MEDARDE, ANTONIO, CANEDO HERNANDEZ, LIBRADA MARIA, GARCIA CABALLERO, MELISSA, VINUESA-NAVARRO, MARIA DE LOS ANGELES
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention refers to compounds of general formula (I) wherein the variables take the various meanings, pharmaceutical compositions containing them and their use in medicine: The compounds have shown to be useful in therapy as angiogenesis inhibitors. The compounds are isolated from the fermentation broth of a fungal strain Paraconiothyrium sp., or are derivatives thereof.