SALTS OF 2-AMINO-1-HYDROXYETHYL-8-HYDROXYQUINOLIN-2(1H)-ONE DERIVATIVES HAVING BOTH MUSCARINIC RECEPTOR ANTAGONIST AND .BETA.2 ADRENERGIC RECEPTOR AGONIST ACTIVITIES
ABSTRACT The present invention is directed to pharmaceutically acceptable crystalline addition salts of 2-amino-1-hydroxyethyl-8-hydroxyquinolin-2(1H)-one derivatives of formula (l) or pharmaceutically acceptable solvates thereof: R4 R5 OH 0 V, R6 R1 R2 7 C5 HO HN M R3 0 Formula (l) The provided pha...
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| creator | CARRERA CARRERA, FRANCESC PRAT QUINONES, MARIA JULIA JANE, MONTSERRAT PAJUELO LORENZO, FRANCESCA PUIG DURAN, CARLOS PEREZ ANDRES, JUAN ANTONIO |
| description | ABSTRACT The present invention is directed to pharmaceutically acceptable crystalline addition salts of 2-amino-1-hydroxyethyl-8-hydroxyquinolin-2(1H)-one derivatives of formula (l) or pharmaceutically acceptable solvates thereof: R4 R5 OH 0 V, R6 R1 R2 7 C5 HO HN M R3 0 Formula (l) The provided pharmaceutically acceptable crystalline addition salts are stable, and have relatively high melting point. CPST Doc: 260697.1 Date Recue/Date Received 2020-06-05
La présente invention concerne des sels d'addition cristallins (i) de dérivés 8-hydroxyquinolin- 2(1H)-one et (ii) d'un acide dicarboxylique ou d'un sulfimide, ou des solvates pharmaceutiquement acceptables de ceux-ci. |
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La présente invention concerne des sels d'addition cristallins (i) de dérivés 8-hydroxyquinolin- 2(1H)-one et (ii) d'un acide dicarboxylique ou d'un sulfimide, ou des solvates pharmaceutiquement acceptables de ceux-ci.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210622&DB=EPODOC&CC=CA&NR=2917596C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210622&DB=EPODOC&CC=CA&NR=2917596C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CARRERA CARRERA, FRANCESC</creatorcontrib><creatorcontrib>PRAT QUINONES, MARIA</creatorcontrib><creatorcontrib>JULIA JANE, MONTSERRAT</creatorcontrib><creatorcontrib>PAJUELO LORENZO, FRANCESCA</creatorcontrib><creatorcontrib>PUIG DURAN, CARLOS</creatorcontrib><creatorcontrib>PEREZ ANDRES, JUAN ANTONIO</creatorcontrib><title>SALTS OF 2-AMINO-1-HYDROXYETHYL-8-HYDROXYQUINOLIN-2(1H)-ONE DERIVATIVES HAVING BOTH MUSCARINIC RECEPTOR ANTAGONIST AND .BETA.2 ADRENERGIC RECEPTOR AGONIST ACTIVITIES</title><description>ABSTRACT The present invention is directed to pharmaceutically acceptable crystalline addition salts of 2-amino-1-hydroxyethyl-8-hydroxyquinolin-2(1H)-one derivatives of formula (l) or pharmaceutically acceptable solvates thereof: R4 R5 OH 0 V, R6 R1 R2 7 C5 HO HN M R3 0 Formula (l) The provided pharmaceutically acceptable crystalline addition salts are stable, and have relatively high melting point. CPST Doc: 260697.1 Date Recue/Date Received 2020-06-05
La présente invention concerne des sels d'addition cristallins (i) de dérivés 8-hydroxyquinolin- 2(1H)-one et (ii) d'un acide dicarboxylique ou d'un sulfimide, ou des solvates pharmaceutiquement acceptables de ceux-ci.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFjL0OAUEUhbdRCJ7BLSlGsiv-ymv22rnJmmHm2thKREYlSHgl72kLCpXqnJPvy2knr4ClBHAryBSu2TqVKlPn3u1rElOXav6d211DS7YqG6RmqJwlyMlzhcIVBTBYsS1g6cTAehc0eraswZOmjTgPaAULZzlIU3MYLUlwlAHmniz54kf9erq5ZmEK3aR1Pl4esffJTtJfkWij4v12iI_78RSv8XnQmC3S2WQx1eP_xhumGEVg</recordid><startdate>20210622</startdate><enddate>20210622</enddate><creator>CARRERA CARRERA, FRANCESC</creator><creator>PRAT QUINONES, MARIA</creator><creator>JULIA JANE, MONTSERRAT</creator><creator>PAJUELO LORENZO, FRANCESCA</creator><creator>PUIG DURAN, CARLOS</creator><creator>PEREZ ANDRES, JUAN ANTONIO</creator><scope>EVB</scope></search><sort><creationdate>20210622</creationdate><title>SALTS OF 2-AMINO-1-HYDROXYETHYL-8-HYDROXYQUINOLIN-2(1H)-ONE DERIVATIVES HAVING BOTH MUSCARINIC RECEPTOR ANTAGONIST AND .BETA.2 ADRENERGIC RECEPTOR AGONIST ACTIVITIES</title><author>CARRERA CARRERA, FRANCESC ; PRAT QUINONES, MARIA ; JULIA JANE, MONTSERRAT ; PAJUELO LORENZO, FRANCESCA ; PUIG DURAN, CARLOS ; PEREZ ANDRES, JUAN ANTONIO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2917596C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2021</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>CARRERA CARRERA, FRANCESC</creatorcontrib><creatorcontrib>PRAT QUINONES, MARIA</creatorcontrib><creatorcontrib>JULIA JANE, MONTSERRAT</creatorcontrib><creatorcontrib>PAJUELO LORENZO, FRANCESCA</creatorcontrib><creatorcontrib>PUIG DURAN, CARLOS</creatorcontrib><creatorcontrib>PEREZ ANDRES, JUAN ANTONIO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CARRERA CARRERA, FRANCESC</au><au>PRAT QUINONES, MARIA</au><au>JULIA JANE, MONTSERRAT</au><au>PAJUELO LORENZO, FRANCESCA</au><au>PUIG DURAN, CARLOS</au><au>PEREZ ANDRES, JUAN ANTONIO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SALTS OF 2-AMINO-1-HYDROXYETHYL-8-HYDROXYQUINOLIN-2(1H)-ONE DERIVATIVES HAVING BOTH MUSCARINIC RECEPTOR ANTAGONIST AND .BETA.2 ADRENERGIC RECEPTOR AGONIST ACTIVITIES</title><date>2021-06-22</date><risdate>2021</risdate><abstract>ABSTRACT The present invention is directed to pharmaceutically acceptable crystalline addition salts of 2-amino-1-hydroxyethyl-8-hydroxyquinolin-2(1H)-one derivatives of formula (l) or pharmaceutically acceptable solvates thereof: R4 R5 OH 0 V, R6 R1 R2 7 C5 HO HN M R3 0 Formula (l) The provided pharmaceutically acceptable crystalline addition salts are stable, and have relatively high melting point. CPST Doc: 260697.1 Date Recue/Date Received 2020-06-05
La présente invention concerne des sels d'addition cristallins (i) de dérivés 8-hydroxyquinolin- 2(1H)-one et (ii) d'un acide dicarboxylique ou d'un sulfimide, ou des solvates pharmaceutiquement acceptables de ceux-ci.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | SALTS OF 2-AMINO-1-HYDROXYETHYL-8-HYDROXYQUINOLIN-2(1H)-ONE DERIVATIVES HAVING BOTH MUSCARINIC RECEPTOR ANTAGONIST AND .BETA.2 ADRENERGIC RECEPTOR AGONIST ACTIVITIES |
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