5,6,7,8-TETRAHYDROPYRAZINO[2,3-C]PYRIDAZINE COMPOUNDS AND THE USE THEREOF TO TREAT ONCOLOGICAL DISEASES

The invention relates to novel chemical compounds of general formula I, in which L A, L B, L C, ring A, ring B, R A, R B, R C,R D,R E and R F have are defined in the description, and which are protein kinases inhibitors. The invention also relates to pharmaceutical compositions containing said compo...

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Bibliographische Detailangaben
Hauptverfasser:	CHILOV, GERMES GRIGORIEVICH, STROILOV, VIKTOR SERGEEVICH, STROGANOV, OLEG VALENTINOVICH, TITOV, ILYA YURIEVICH, NOVIKOV, FEDOR NIKOLAEVICH, ZEIFMAN, ALEKSEY ALEXANDROVICH
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to novel chemical compounds of general formula I, in which L A, L B, L C, ring A, ring B, R A, R B, R C,R D,R E and R F have are defined in the description, and which are protein kinases inhibitors. The invention also relates to pharmaceutical compositions containing said compounds and also to the use of said compounds for treatment and/or prevention of diseases related with aberrant protein kinase activity. (see formula I)