HETEROCYCLIC DERIVATIVES AND USE THEREOF

ABSTRACT A heterocyclic derivative represented by formula (I) (R3), (R4)5 X2 y (Ri)p - , X3, = X5 NI L = (R2),, or a pharmaceutically acceptable salt or a stereoisomer thereof, which has an inhibitory effect on the activation of STAT3 protein, and is useful for the prevention or treatment of disease...

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Hauptverfasser: KO, KWANG SEOK, LEE, SANG HWI, IM, JUNHWAN, KIM, JONGMIN, KIM, BYUNGHO, KIM, HOE MOON, CHOI, BU YOUNG, MOON, SUNG HYUN, PARK, CHAN HEE, LEE, SOON OK, KIM, SEUNGHEE
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:ABSTRACT A heterocyclic derivative represented by formula (I) (R3), (R4)5 X2 y (Ri)p - , X3, = X5 NI L = (R2),, or a pharmaceutically acceptable salt or a stereoisomer thereof, which has an inhibitory effect on the activation of STAT3 protein, and is useful for the prevention or treatment of diseases associated with the activation of STAT3 protein. Date Recue/Date Received 2020-07-31 L'invention concerne un dérivé hétérocyclique représenté par la formule (I), ou un sel pharmaceutiquement acceptable ou un stéréoisomère de celui-ci, qui a un effet inhibiteur sur l'activation de la protéine STAT3, et est utile dans la prévention ou le traitement de maladies associées à l'activation de la protéine STAT3.