3,4-DIHYDRO-2H-ISOQUINOLINE-1-ONE AND 2,3-DIHYDRO-ISOINDOL-1-ONE COMPOUNDS

3,4-DIHYDRO-2H-ISOQUINOLINE-1-ONE AND 2,3-DIHYDRO-ISOINDOL-1-ONE COMPOUNDS

The invention provides novel compounds having the general formula (I) including pharmaceutically acceptable salts thereof, pharmaceutical compositions including these compounds, processes for their preparation, and methods of using the compounds. Uses include, for example, for treatment or prophylax...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: CHEN, WENMING, AMREIN, KURT, LIU, YONGFU, AEBI, JOHANNES, HORNSPERGER, BENOIT, MAERKI, HANS P, MARTIN, RAINER E, TAN, XUEFEI, WANG, LISHA, ZHOU, MINGWEI, KUHN, BERND, MAYWEG, ALEXANDER V, LI, DONGBO, WU, JUN
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention provides novel compounds having the general formula (I) including pharmaceutically acceptable salts thereof, pharmaceutical compositions including these compounds, processes for their preparation, and methods of using the compounds. Uses include, for example, for treatment or prophylaxis of chronic kidney disease, congestive heart failure, hypertension, primary aldosteronism or Cushing syndrome. L'invention concerne de nouveaux composés ayant la formule générale (I), dans laquelle R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, A, B, m, n et p sont tels que décrits ici, des compositions comprenant les composés et des procédés d'utilisation des composés.