CFTR MRNA COMPOSITIONS AND RELATED METHODS AND USES

Materials, formulations, production methods, and methods for delivery of CFTR mRNA for induction of CFTR expression, including in the mammalian lung are provided. The present invention is particularly useful for treating cystic fibrosis. La présente invention concerne des matériaux, des compositions...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	GUILD, BRAYDON CHARLES, HEARTLEIN, MICHAEL, SMITH, LIANNE, PLANK, CHRISTIAN, DEROSA, FRANK, RUDOLPH, CARSTEN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

container_end_page
container_issue
container_start_page
container_title
container_volume
creator	GUILD, BRAYDON CHARLES HEARTLEIN, MICHAEL SMITH, LIANNE PLANK, CHRISTIAN DEROSA, FRANK RUDOLPH, CARSTEN
description	Materials, formulations, production methods, and methods for delivery of CFTR mRNA for induction of CFTR expression, including in the mammalian lung are provided. The present invention is particularly useful for treating cystic fibrosis. La présente invention concerne des matériaux, des compositions, des procédés de production et des procédés d'administration d'ARNm du gène CFTR en vue de l'induction de l'expression de la protéine CFTR, y compris dans les poumons d'un mammifère. La présente invention se révèle particulièrement utile dans le cadre du traitement de la mucoviscidose.
format	Patent
fullrecord	<record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CA2904151C</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CA2904151C</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CA2904151C3</originalsourceid><addsrcrecordid>eNrjZDB2dgsJUvAN8nNUcPb3DfAP9gzx9PcLVnD0c1EIcvVxDHF1UfB1DfHwd4GIhQa7BvMwsKYl5hSn8kJpbgZ5N9cQZw_d1IL8-NTigsTk1LzUknhnRyNLAxNDU0NnY8IqAPwaJgs</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>CFTR MRNA COMPOSITIONS AND RELATED METHODS AND USES</title><source>esp@cenet</source><creator>GUILD, BRAYDON CHARLES ; HEARTLEIN, MICHAEL ; SMITH, LIANNE ; PLANK, CHRISTIAN ; DEROSA, FRANK ; RUDOLPH, CARSTEN</creator><creatorcontrib>GUILD, BRAYDON CHARLES ; HEARTLEIN, MICHAEL ; SMITH, LIANNE ; PLANK, CHRISTIAN ; DEROSA, FRANK ; RUDOLPH, CARSTEN</creatorcontrib><description>Materials, formulations, production methods, and methods for delivery of CFTR mRNA for induction of CFTR expression, including in the mammalian lung are provided. The present invention is particularly useful for treating cystic fibrosis. La présente invention concerne des matériaux, des compositions, des procédés de production et des procédés d'administration d'ARNm du gène CFTR en vue de l'induction de l'expression de la protéine CFTR, y compris dans les poumons d'un mammifère. La présente invention se révèle particulièrement utile dans le cadre du traitement de la mucoviscidose.</description><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230912&DB=EPODOC&CC=CA&NR=2904151C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230912&DB=EPODOC&CC=CA&NR=2904151C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>GUILD, BRAYDON CHARLES</creatorcontrib><creatorcontrib>HEARTLEIN, MICHAEL</creatorcontrib><creatorcontrib>SMITH, LIANNE</creatorcontrib><creatorcontrib>PLANK, CHRISTIAN</creatorcontrib><creatorcontrib>DEROSA, FRANK</creatorcontrib><creatorcontrib>RUDOLPH, CARSTEN</creatorcontrib><title>CFTR MRNA COMPOSITIONS AND RELATED METHODS AND USES</title><description>Materials, formulations, production methods, and methods for delivery of CFTR mRNA for induction of CFTR expression, including in the mammalian lung are provided. The present invention is particularly useful for treating cystic fibrosis. La présente invention concerne des matériaux, des compositions, des procédés de production et des procédés d'administration d'ARNm du gène CFTR en vue de l'induction de l'expression de la protéine CFTR, y compris dans les poumons d'un mammifère. La présente invention se révèle particulièrement utile dans le cadre du traitement de la mucoviscidose.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDB2dgsJUvAN8nNUcPb3DfAP9gzx9PcLVnD0c1EIcvVxDHF1UfB1DfHwd4GIhQa7BvMwsKYl5hSn8kJpbgZ5N9cQZw_d1IL8-NTigsTk1LzUknhnRyNLAxNDU0NnY8IqAPwaJgs</recordid><startdate>20230912</startdate><enddate>20230912</enddate><creator>GUILD, BRAYDON CHARLES</creator><creator>HEARTLEIN, MICHAEL</creator><creator>SMITH, LIANNE</creator><creator>PLANK, CHRISTIAN</creator><creator>DEROSA, FRANK</creator><creator>RUDOLPH, CARSTEN</creator><scope>EVB</scope></search><sort><creationdate>20230912</creationdate><title>CFTR MRNA COMPOSITIONS AND RELATED METHODS AND USES</title><author>GUILD, BRAYDON CHARLES ; HEARTLEIN, MICHAEL ; SMITH, LIANNE ; PLANK, CHRISTIAN ; DEROSA, FRANK ; RUDOLPH, CARSTEN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2904151C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2023</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>GUILD, BRAYDON CHARLES</creatorcontrib><creatorcontrib>HEARTLEIN, MICHAEL</creatorcontrib><creatorcontrib>SMITH, LIANNE</creatorcontrib><creatorcontrib>PLANK, CHRISTIAN</creatorcontrib><creatorcontrib>DEROSA, FRANK</creatorcontrib><creatorcontrib>RUDOLPH, CARSTEN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>GUILD, BRAYDON CHARLES</au><au>HEARTLEIN, MICHAEL</au><au>SMITH, LIANNE</au><au>PLANK, CHRISTIAN</au><au>DEROSA, FRANK</au><au>RUDOLPH, CARSTEN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>CFTR MRNA COMPOSITIONS AND RELATED METHODS AND USES</title><date>2023-09-12</date><risdate>2023</risdate><abstract>Materials, formulations, production methods, and methods for delivery of CFTR mRNA for induction of CFTR expression, including in the mammalian lung are provided. The present invention is particularly useful for treating cystic fibrosis. La présente invention concerne des matériaux, des compositions, des procédés de production et des procédés d'administration d'ARNm du gène CFTR en vue de l'induction de l'expression de la protéine CFTR, y compris dans les poumons d'un mammifère. La présente invention se révèle particulièrement utile dans le cadre du traitement de la mucoviscidose.</abstract><oa>free_for_read</oa></addata></record>
fulltext	fulltext_linktorsrc
identifier
ispartof
issn
language	eng ; fre
recordid	cdi_epo_espacenet_CA2904151C
source	esp@cenet
subjects	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
title	CFTR MRNA COMPOSITIONS AND RELATED METHODS AND USES
url	https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-25T20%3A55%3A21IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=GUILD,%20BRAYDON%20CHARLES&rft.date=2023-09-12&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECA2904151C%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true