3,4-DIHYDRO-2H-ISOQUINOLINE-1-ONE AND 2,3-DIHYDRO-ISOINDOL-1-ONE COMPOUNDS

The invention provides novel compounds having the general formula (I) including pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising these compounds, processes for their production, and methods of using the compounds. Such uses include, for example, for the treatment or...

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Bibliographische Detailangaben
Hauptverfasser:	MAERKI, HANS P, MARTIN, RAINER E, TAN, XUEFEI, CHEN, WENMING, AMREIN, KURT, LIU, YONGFU, WANG, LISHA, ZHOU, MINGWEI, AEBI, JOHANNES, HORNSPERGER, BENOIT, KUHN, BERND, MAYWEG, ALEXANDER V
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention provides novel compounds having the general formula (I) including pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising these compounds, processes for their production, and methods of using the compounds. Such uses include, for example, for the treatment or prophylaxis of chronic kidney disease, congestive heart failure, hypertension, primary aldosteronism or Cushing syndrome. L'invention concerne de nouveaux composés de formule générale (I) comprenant des sels acceptables sur le plan pharmaceutique, des compositions pharmaceutiques comprenant lesdits composés, leurs procédés de fabrication et des méthodes d'utilisation. Les utilisations comprennent, par exemple, le traitement ou la prophylaxie de la néphropathie chronique, l'insuffisance cardiaque congestive, l'hypertension, l'aldostéronisme primaire ou le syndrome de Cushing.