AMIDES AS MODULATORS OF SODIUM CHANNELS
The invention relates to amide compounds of formulae I and I': and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the composit...
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| creator | JOHNSON, JAMES PHILIP TERMIN, ANDREAS P HADIDA-RUAH, SARA SABINA BEAR, BRIAN RICHARD ARUMUGAM, VIJAYALAKSMI ASGIAN, IULIANA LUCI ANDERSON, COREY |
| description | The invention relates to amide compounds of formulae I and I': and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders, including pain.
L'invention concerne des composés d'amide de la formule I et des sels de qualité pharmaceutique de ceux-ci, utiles comme inhibiteurs des canaux sodiques : (I), (I'). L'invention concerne également des compositions de qualité pharmaceutique comportant les composés de l'invention et des procédés d'utilisation des compositions dans le traitement de divers troubles, comprenant la douleur. |
| format | Patent |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | AMIDES AS MODULATORS OF SODIUM CHANNELS |
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