COMBINATIONS OF A GLP1R AGONIST AND METFORMIN AND USE THEREOF FOR THE TREATMENT OF TYPE 2 DIABETES AND OTHER DISORDERS

The present invention provides uses of a glucagon-like peptide 1 receptor agonist in combination with metformin. Uses include treating type 2 diabetes, lowering blood glucose, and improving the therapeutic effectiveness of metformin. The invention also provides pharmaceutical compositions that compr...

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Bibliographische Detailangaben
Hauptverfasser:	CLARK, BRADLEY ALAN, VALCARCE LOPEZ, MARIA CARMEN, DAVIS, STEPHEN THOMAS, POLISETTI, DHARMA RAO, YOKUM, THOMAS SCOTT, MJALLI, ADNAN M.M, ANDREWS, ROBERT CARL, QUADA, JAMES C
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides uses of a glucagon-like peptide 1 receptor agonist in combination with metformin. Uses include treating type 2 diabetes, lowering blood glucose, and improving the therapeutic effectiveness of metformin. The invention also provides pharmaceutical compositions that comprise a GLP1R agonist and metformin. La présente invention concerne des utilisations d'un agoniste du récepteur du peptide 1 analogue au glucagon en combinaison avec de la metformine. Des utilisations incluent le traitement du diabète de type 2, l'abaissement du glucose sanguin et l'amélioration de l'efficacité thérapeutique de la metformine. L'invention concerne également des compositions pharmaceutiques qui comprennent un agoniste du GLP1R et de la metformine.