MODULATED LYSINE VARIANT SPECIES COMPOSITIONS AND METHODS FOR PRODUCING AND USING THE SAME

The instant invention relates to modulated lysine variant species compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods, e.g., cell culture and/or protein purification methods, for producing such modulated Lysine compositions. Methods for using such co...

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Hauptverfasser: JING, YING, WONG, CHEE FURNG, PEREZ THIELE, MAYDA, ZENG, XIAOBEI, KAYMAKCALAN, ZEHRA, CHUMSAE, CHRISTOPHER, SUBRAMANIAN, KARTIK
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creator JING, YING
WONG, CHEE FURNG
PEREZ THIELE, MAYDA
ZENG, XIAOBEI
KAYMAKCALAN, ZEHRA
CHUMSAE, CHRISTOPHER
SUBRAMANIAN, KARTIK
description The instant invention relates to modulated lysine variant species compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods, e.g., cell culture and/or protein purification methods, for producing such modulated Lysine compositions. Methods for using such compositions to treat a disorder, e.g., a disorder in which TNFa is detrimental, are also provided.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title MODULATED LYSINE VARIANT SPECIES COMPOSITIONS AND METHODS FOR PRODUCING AND USING THE SAME
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