NOVEL BENZIMIDAZOLE DERIVATIVES AS EP4 ANTAGONISTS

The present invention relates to compounds of the general formula (l): in which R1a, R1b and R4 are H, alkyl, etc.; R6 is H, halo etc; A is an ester group and B is a heterocyclic moiety, processes for their preparation and their use for the production of pharmaceutical compositions for the treatment...

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Bibliographische Detailangaben
Hauptverfasser:	BLUME, THORSTEN, KAULFUSS, STEFAN, LANGER, GERNOT, PETERS, OLAF, KUHNKE, JOACHIM, NAGEL, JENS, BRAUER, NICO, TER LAAK, ANTONIUS, ZORN, LUDWIG
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to compounds of the general formula (l): in which R1a, R1b and R4 are H, alkyl, etc.; R6 is H, halo etc; A is an ester group and B is a heterocyclic moiety, processes for their preparation and their use for the production of pharmaceutical compositions for the treatment of diseases and indications that are connected with the receptor EP4. L'invention concerne de nouveaux dérivés du benzimidazole de la formule générale (I), des procédés pour leur préparation et leur utilisation à la préparation de produits pharmaceutiques pour le traitement d'affection et pour des indications en rapport avec le récepteur EP4.