SURFACE MODIFICATION OF POROUS BASE SUPPORTS

The present invention relates to new separation materials for affinity chromatography with improved binding capacity based on hydroxyl-containing porous base supports onto which polymer chains are grafted by covalent bonding via OH groups present on the surface of the base support, their manufacturi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SCHEID, DANIEL, BIAN, NANYING, RAHANE, SANTOSH
Format: Patent
Sprache:eng ; fre
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Beschreibung
Zusammenfassung:The present invention relates to new separation materials for affinity chromatography with improved binding capacity based on hydroxyl-containing porous base supports onto which polymer chains are grafted by covalent bonding via OH groups present on the surface of the base support, their manufacturing, and use, especially for binding protein A. La présente invention concerne de nouveaux matériels de séparation possédant une capacité de liaison améliorée, leur fabrication et leur application, notamment pour la liaison à la protéine A.