NITROGEN-BASED HETEROCYCLOALKYL DERIVATIVES AS INHIBITORS OF THE ENZYME FABI

The present invention is related to compounds of formula (I) that may inhibit the activity of the FabI enzyme, and which are useful in the treatment of bacterial infections. It further relates to pharmaceutical compositions comprising these compounds, and chemical processes for preparing these compo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	BALEMANS, WENDY MIA ALBERT, LANCOIS, DAVID FRANCIS ALAIN, KOUL, ANIL, GUILLEMONT, JEROME EMILE GEORGES, MOTTE, MAGALI MADELEINE SIMONE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention is related to compounds of formula (I) that may inhibit the activity of the FabI enzyme, and which are useful in the treatment of bacterial infections. It further relates to pharmaceutical compositions comprising these compounds, and chemical processes for preparing these compounds. La présente invention concerne de nouveaux composés de formule (I) qui peuvent inhiber l'activité de l'enzyme FabI, et qui sont utiles dans le traitement d'infections bactériennes. L'invention concerne en outre des compositions pharmaceutiques comprenant ces composés, et des procédés chimiques pour la préparation de ces composés.