CRYSTALLINE MICROSPHERES AND THE PROCESS FOR MANUFACTURING THE SAME

The present invention relates to microspheres and compositions comprising a plurality of microspheres, wherein the microspheres are perfectly spherical and have a moisture content less than 1%, and the method of manufacturing the same. The present invention is useful in the manufacture of sustained...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MEADOWS, MARC W, PROPST, CECIL W, TODD, MICHAEL S
Format: Patent
Sprache:eng ; fre
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Beschreibung
Zusammenfassung:The present invention relates to microspheres and compositions comprising a plurality of microspheres, wherein the microspheres are perfectly spherical and have a moisture content less than 1%, and the method of manufacturing the same. The present invention is useful in the manufacture of sustained and modified release active pharmaceutical ingredient (API) microspheres, as a free flowing excipient for mini-tablets and in the manufacture of API dispersions.