THIADIAZOLIDINEDIONES AS GSK-3 INHIBITORS

The present invention relates to new thiadiazolidmediones of formula (I), or any pharmaceutically acceptable salt, solvate or prodrug thereof, and its use in the treatment of a disease in which glycogen synthase kinase 3 (GSK-3) is involved, particularly neurodegenerative diseases, inflammatory and...

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Bibliographische Detailangaben
Hauptverfasser:	DOMINGUEZ CORREA, JUAN MANUEL, PALOMO NICOLAU, FRANCISCO, DE CRISTOBAL BLANCO, JAVIER, LOPEZ OGALLA, JAVIER, HERRERO SANTOS, SUSANA, MARTINEZ MONTERO, OLGA, RODRIGUEZ SALGUERO, BEATRIZ, SANCHEZ-QUESADA, JORGE, MEDINA PADILLA, MIGUEL, PEREZ DE LA CRUZ MORENO, MARIA ANGELES, FUERTES HUERTA, ANA
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to new thiadiazolidmediones of formula (I), or any pharmaceutically acceptable salt, solvate or prodrug thereof, and its use in the treatment of a disease in which glycogen synthase kinase 3 (GSK-3) is involved, particularly neurodegenerative diseases, inflammatory and autoimmune diseases and cardiovascular disorders. Additionally, there is provided a process for preparing such compounds, as well as pharmaceutical compositions comprising them.