SALTS OF A DIHYDROQUINAZOLINE DERIVATIVE

The invention relates to sodium and calcium salts of {8-fluoro-2-[4- (3-methoxyphenyl)piperazine-1-yl]-3-[2-methoxy-5-(trifluoromethyl) phenyl]-3,4-dihydroquinazoline-4-yl}acetic acid and solvates thereof, to the use thereof for treatment and/or prophylaxis of viral infections and to the use thereof...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	KEIL, BIRGIT, PAULUS, KERSTIN, GRUNENBERG, ALFONS, BERWE, MATHIAS, ARET, EDWIN, SCHWAB, WILFRIED
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to sodium and calcium salts of {8-fluoro-2-[4- (3-methoxyphenyl)piperazine-1-yl]-3-[2-methoxy-5-(trifluoromethyl) phenyl]-3,4-dihydroquinazoline-4-yl}acetic acid and solvates thereof, to the use thereof for treatment and/or prophylaxis of viral infections and to the use thereof for producing pharmaceuticals for treatment and/or prophylaxis of diseases, more particularly the use thereof as antiviral agents, more particularly against cytomegaloviruses. L'invention concerne des sels de sodium et de calcium d'acide acétique {8-fluoro-2-[4- (3-méthoxyphényl)pipérazine-1-yle]-3-[2-méthoxy-5-(trifluorméthyl) phényl]-3,4-dihydroquinazoline-4-yle} et des solvates de ceux-ci, leur utilisation pour le traitement thérapeutique et/ou prophylactique d'infections virales et leur utilisation dans la fabrication de médicaments destinés au traitement thérapeutique et/ou prophylactique de maladies, notamment leur utilisation en qu'agents antiviraux, en particulier pour lutter contre les cytomégalovirus.