DYNAMIC CONTRAST ENHANCED-MRI METHOD AND AGENTS FOR THE ASSESSMENT OF THE MACROMOLECULAR TRANSPORT WITHIN PATHOLOGIC TISSUES

DYNAMIC CONTRAST ENHANCED-MRI METHOD AND AGENTS FOR THE ASSESSMENT OF THE MACROMOLECULAR TRANSPORT WITHIN PATHOLOGIC TISSUES

The present invention generally relates to paramagnetic contrast agents and a Dynamic Contrast Enhanced-MRI method for the non-invasive estimation of the delivery of a macromolecular anticancer drug or pro-drug within pathological tissues and, especially, in solid tumors and for the optimization of...

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Bibliographische Detailangaben
Hauptverfasser: MOSCHETTA, MICHELE, GIAVAZZI, RAFFAELLA, VALBUSA, GIOVANNI, MAIOCCHI, ALESSANDRO
Format: Patent
Sprache:eng ; fre
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:The present invention generally relates to paramagnetic contrast agents and a Dynamic Contrast Enhanced-MRI method for the non-invasive estimation of the delivery of a macromolecular anticancer drug or pro-drug within pathological tissues and, especially, in solid tumors and for the optimization of anticancer therapies.