PROCESSES USING VLPS WITH CAPSIDS RESISTANT TO HYDROLASES

Novel processes and compositions are described which use viral capsid proteins resistant to hydrolases to prepare virus-like particles to enclose and subsequently isolate and purify target cargo molecules of interest including nucleic acids such as siRNA's and shRNA's, and small peptides....

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Hauptverfasser: DELANEY, KIMBERLY, SUMMERS, NEENA, ARHANCET, JUAN P, HALL, KATHLEEN B, ARHANCET, JUAN PEDRO HUMBERTO
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creator DELANEY, KIMBERLY
SUMMERS, NEENA
ARHANCET, JUAN P
HALL, KATHLEEN B
ARHANCET, JUAN PEDRO HUMBERTO
description Novel processes and compositions are described which use viral capsid proteins resistant to hydrolases to prepare virus-like particles to enclose and subsequently isolate and purify target cargo molecules of interest including nucleic acids such as siRNA's and shRNA's, and small peptides. La présente invention concerne de nouveaux procédés et compositions qui utilisent des protéines de capside viral résistantes aux hydrolases pour préparer des particules de type viral pour encapsuler et ensuite isoler et purifier des molécules d'intérêt de charge cibles comprenant des acides nucléiques tels que des ARNsi et des ARNsh et des petits peptides.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
DERIVATIVES THEREOF
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
SUGARS
VINEGAR
WINE
title PROCESSES USING VLPS WITH CAPSIDS RESISTANT TO HYDROLASES
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