INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATION
The inventive compounds are small molecule therapeutics that are potent inhibitors of Arginase I and II activity. The invention also provides pharmaceutical compositions of the inventive compounds and methods for using the inventive compounds for treating or preventing a disease or a condition assoc...
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| creator | WHITEHOUSE, DARREN VAN ZANDT, MICHAEL GOLEBIOWSKI, ADAM RYDER, TODD BECKETT, RAYMOND PAUL JI, MIN KOO |
| description | The inventive compounds are small molecule therapeutics that are potent inhibitors of Arginase I and II activity. The invention also provides pharmaceutical compositions of the inventive compounds and methods for using the inventive compounds for treating or preventing a disease or a condition associated with arginase activity.
Les composés selon l'invention sont des agents thérapeutiques à petite molécule qui sont de puissants inhibiteurs de l'activité de l'arginase I et II. L'invention concerne également des compositions pharmaceutiques contenant ces composés, ainsi que des procédés d'utilisation des composés selon l'invention pour le traitement ou la prévention d'une maladie ou d'une affection associée à l'activité de l'arginase. |
| format | Patent |
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| subjects | ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATION |
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