DETECTION OF ISOTYPE PROFILES AS SIGNATURES FOR DISEASE

DETECTION OF ISOTYPE PROFILES AS SIGNATURES FOR DISEASE

The invention provides a non-invasive technique for the detection and quantification of immune globulin isotypes, in a biological sample containing a plurality of distinct cell populations. Methods are conducted using sequencing technology to detect and enumerate immunoglobulin isotype profiles with...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HUTCHINS, MARIA U, SELIGSON, DANIEL
Format: Patent
Sprache:eng ; fre
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:The invention provides a non-invasive technique for the detection and quantification of immune globulin isotypes, in a biological sample containing a plurality of distinct cell populations. Methods are conducted using sequencing technology to detect and enumerate immunoglobulin isotype profiles within a heterogeneous biological sample. Cette invention concerne une technique non invasive permettant de détecter et de quantifier les isotypes d'immunoglobulines dans un échantillon biologique contenant plusieurs populations cellulaires distinctes. Les méthodes sont réalisées en utilisant le séquençage pour détecter et énumérer les profils des isotypes d'immunoglobulines dans un échantillon biologique hétérogène.