PROCESS FOR STEREOSELECTIVE SYNTHESIS OF PROSTACYCLIN DERIVATIVES

An improved method is described for making 9-deoxy-PGF1-type compounds particularly prostacyclin derivatives and novel intermediate compounds useful in the process. In contrast to the prior art, the method is stereoselective and requires fewer steps than the known methods for making these compounds....

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	RAO, MUNAGALA S, GUO, LIANG, STASZEWSKI, JAMES P, PENMASTA, RAJU, MORIARTY, ROBERT M
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM APPARATUS THEREFOR CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	An improved method is described for making 9-deoxy-PGF1-type compounds particularly prostacyclin derivatives and novel intermediate compounds useful in the process. In contrast to the prior art, the method is stereoselective and requires fewer steps than the known methods for making these compounds. A compound of the of the formula: (see above formula) is disclosed.