TRANSGENIC ANIMALS BEARING HUMAN IG.LAMBDA. LIGHT CHAIN GENES

The invention relates to transgenic animals bearing one or more human .lambda. light chain loci. The invention also relates to methods and compositions for making transgenic animals that have incorporated human .lambda. light chain loci. The invention further relates to methods of using and composit...

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Bibliographische Detailangaben
Hauptverfasser:	GREEN, LARRY L, IVANOV, VLADIMIR
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BEER BIOCHEMISTRY CARE OF BIRDS, FISHES, INSECTS CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE FISHING FORESTRY HUMAN NECESSITIES HUNTING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NEW BREEDS OF ANIMALS ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR SPIRITS TRAPPING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to transgenic animals bearing one or more human .lambda. light chain loci. The invention also relates to methods and compositions for making transgenic animals that have incorporated human .lambda. light chain loci. The invention further relates to methods of using and compositions derived from the transgenic animals that have incorporated human .lambda. light chain loci. Linvention concerne des animaux transgéniques portant un ou plusieurs locus lambda de chaînes légères des immunoglobulines humaines. Linvention concerne également des méthodes et des compositions pour créer des animaux transgéniques qui ont incorporé des locus lambda de chaînes légères des immunoglobulines humaines. Linvention concerne également des méthodes dutilisation et des compositions dérivées des animaux transgéniques qui ont incorporé des locus lambda de chaînes légères des immunoglobulines humaines.