1-PYRAZOLYL-3-(4-((2-ANILINOPYRIMIDIN-4-YL)OXY)NAPTHTHALEN-1- YL) UREAS AS P38 MAP KINASE INHIBITORS

1-PYRAZOLYL-3-(4-((2-ANILINOPYRIMIDIN-4-YL)OXY)NAPTHTHALEN-1- YL) UREAS AS P38 MAP KINASE INHIBITORS

There is provided a compound of formula (I) which is an inhibitor of the family of p38 mitogen-activated protein kinase enzymes, and to its use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, suc...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: FILLIERS, WALTER, CHARRON, CATHERINE ELISABETH, KING-UNDERWOOD, JOHN, ITO, KAZUHIRO, ONIONS, STUART THOMAS, LONGSHAW, ALISTAIR IAN, BROECKX, RUDY, COPMANS, ALEX
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:There is provided a compound of formula (I) which is an inhibitor of the family of p38 mitogen-activated protein kinase enzymes, and to its use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, such as asthma and COPD. L'invention concerne un composé de formule (I) qui est un inhibiteur de la famille d'enzymes protéine kinases activées par le mitogène p38, et son utilisation en thérapie, y compris dans des combinaisons pharmaceutiques, notamment pour le traitement des maladies inflammatoires, y compris les maladies inflammatoires du poumon, telles que l'asthme et la BPCO.