PROCESS FOR PRODUCING VIRAL ANTIGEN AND VACCINES

The present invention belongs to the field of pharmaceutical industry and relates to a method for the production of viral antigen derived from enveloped virus, comprising the steps of providing a fluid comprising enveloped virus, clarifying the fluid comprising said enveloped virus, reducing the vol...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	VAN 'T HOF, RON, SHAKER, SABAH, CUI, YI-QING, VAN ROOIJ, GEERTJE JACOBA, THUS, JO, WANG, YIDING
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention belongs to the field of pharmaceutical industry and relates to a method for the production of viral antigen derived from enveloped virus, comprising the steps of providing a fluid comprising enveloped virus, clarifying the fluid comprising said enveloped virus, reducing the volume of the obtained liquid harvest, solubilizing the enveloped virus, and purifying viral antigen. The present invention further refers to the use of said method for the production of a vaccine preparation. La présente invention appartient au domaine de l'industrie pharmaceutique et concerne un procédé pour la production d'un antigène viral dérivé d'un virus à enveloppe, comprenant les étapes de production d'un fluide comprenant un virus à enveloppe, clarification du fluide comprenant ledit virus à enveloppe, la réduction du volume de la récolte de liquide obtenue, solubilisation du virus à enveloppe, et purification de l'antigène viral. La présente invention concerne en outre l'utilisation dudit procédé pour la production d'une préparation de vaccin.