DEUTERATED 1-PIPERAZINO-3-PHENYL INDANES FOR TREATMENT OF SCHIZOPHRENIA

The present invention relates to deuterated 1-piperazino-3-phenyl-indanes and salts thereof with activity at dopamine receptors D1 and D2 as well as the 5HT2 receptors in the central nervous system, to medicaments comprising such compounds as active ingredients, to the use of such compounds in the t...

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Bibliographische Detailangaben
Hauptverfasser:	JENSEN, KLAUS GJERVIG, BADOLO, LASSINA, ANDERSEN, PETER HONGAARD, JACOBSEN, MIKKEL FOG, HVENEGAARD, METTE GRAULUND, JORGENSEN, MORTEN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	APPARATUS THEREFOR CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to deuterated 1-piperazino-3-phenyl-indanes and salts thereof with activity at dopamine receptors D1 and D2 as well as the 5HT2 receptors in the central nervous system, to medicaments comprising such compounds as active ingredients, to the use of such compounds in the treatment of diseases in the central nervous system, and to methods of treatment comprising administration of such compounds. La présente invention concerne des 1-pipérazino-3-phénylindanes deutérés et des sels de ceux-ci ayant une activité au niveau de récepteurs D1 et D2 dopaminergiques, ainsi qu'au niveau des récepteurs 5HT2 dans le système nerveux central, des médicaments comprenant de tels composés en tant que principes actifs, l'utilisation de tels composés dans le traitement de maladies du système nerveux central, et des méthodes de traitement comprenant l'administration de tels composés.