IONTOPHORESIS DRUG DELIVERY SYSTEM AND METHOD FOR DENERVATION OF THE RENAL SYMPATHETIC NERVE AND IONTOPHORETIC DRUG DELIVERY

An iontophoresis drug delivery system (100) and method for denervation of the renal sympathetic nerve and iontophoresis drug delivery. The system includes an iontophoresis catheter (110) fitted with a drug coated balloon (112). The iontophoresis catheter includes a balloon near its distal tip or end...

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Bibliographische Detailangaben
1. Verfasser:	MEYER, PETER F
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BANDAGES, DRESSINGS OR ABSORBENT PADS DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS ELECTROTHERAPY FILTERS IMPLANTABLE INTO BLOOD VESSELS FIRST-AID KITS FOMENTATION HUMAN NECESSITIES HYGIENE MAGNETOTHERAPY MEDICAL OR VETERINARY SCIENCE ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES PROSTHESES RADIATION THERAPY TREATMENT OR PROTECTION OF EYES OR EARS ULTRASOUND THERAPY
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Beschreibung
Zusammenfassung:	An iontophoresis drug delivery system (100) and method for denervation of the renal sympathetic nerve and iontophoresis drug delivery. The system includes an iontophoresis catheter (110) fitted with a drug coated balloon (112). The iontophoresis catheter includes a balloon near its distal tip or end that contacts the vessel wall circumferentially when inflated. One or more electrodes (118) are associated with a surface of the balloon, and may be disposed on an outer surface of the balloon. The electrodes are operably coupled to an energy source (122) configured to produce a bipolar or monopolar electric field between two balloon electrodes and/or between one balloon electrode and another electrode placed in contact with a part of the patient's body. During use, the disclosed drug-delivery catheter produces an electric potential gradient within adjacent tissue, that, in turn, facilitates iontophoresis delivery of a drug. The disclosed catheter can also include a store of one or more drugs to be delivered to the targeted tissue.