PEPTIDE WHICH CAN INDUCE ANTIBODY CAPABLE OF RECOGNIZING STEREOSTRUCTURE OF HIV

The purpose of the present invention is to provide a peptide which can induce an excellent or novel neutralizing antibody against an HIV, and thereby prevent or treat HIV infection or expand choices of the prevention or treatment. A means for achieving the purpose is characterized by using a peptide...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MIYAUCHI, KOSUKE, TAMAMURA, HIROKAZU, NARUMI, TETSUO, KOMANO, JUN A, HASHIMOTO, CHIE, NOMURA, WATARU
Format: Patent
Sprache:eng ; fre
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Beschreibung
Zusammenfassung:The purpose of the present invention is to provide a peptide which can induce an excellent or novel neutralizing antibody against an HIV, and thereby prevent or treat HIV infection or expand choices of the prevention or treatment. A means for achieving the purpose is characterized by using a peptide which can induce an antibody capable of recognizing the stereostructrue of an HIV, wherein the peptide can recognize a trimeric region in C34 and is characterized in that three molecules of a derivative of a helical region C34 peptide located on the C-terminal side of a transmembrane protein gp41 of an HIV particle are bound together through a template compound that has three equivalent linker structures in a C3 symmetric manner.