TRICYCLIC GYRASE INHIBITORS

(See Formula I) Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors. Related pharmaceutical compositions, uses and methods of making the compounds a...

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Bibliographische Detailangaben
Hauptverfasser:	ZHANG, JUNHU, LEE, SUK JOONG, TRZOSS, MICHAEL, NGUYEN, TOAN B, LI, XIAOMING, CHEN, ZHIYONG, LIGHTSTONE, FELICE, WONG, SERGIO E, BENSEN, DANIEL, PHILLIPSON, DOUGLAS W, LAM, THANH TO, ARISTOFF, PAUL, JUNG, MICHAEL, TARI, LESLIE WILLIAM, FINN, JOHN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	(See Formula I) Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors. Related pharmaceutical compositions, uses and methods of making the compounds are also contemplated. La présente invention concerne des composés qui présentent la structure de la formule I et des sels, des esters et des promédicaments de qualité pharmaceutique de ceux-ci, qui sont utiles en tant qu'inhibiteurs efficaces d'un point de vue antibactérien de la gyrase tricyclique. L'invention concerne des compositions pharmaceutiques associées, des utilisations et des procédés de fabrication des composés.