FLUORO-PYRIDINONE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS

The present invention is directed to a compound to Formula I derivatives, their use as LpxC inhibitors and, more specifically, their use to treat bacterial infections. (see formula I) La présente invention concerne une nouvelle classe de dérivés d'acide hydroxamique, leur utilisation en tant qu...

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Bibliographische Detailangaben
Hauptverfasser:	BROWN, MATHEW FRANK, PRICE, LOREN MICHAEL, MONTGOMERY, JUSTIN IAN, REILLY, USA, MELNICK, MICHAEL JOSEPH, CHE, YE, PLUMMER, MARK STEPHEN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention is directed to a compound to Formula I derivatives, their use as LpxC inhibitors and, more specifically, their use to treat bacterial infections. (see formula I) La présente invention concerne une nouvelle classe de dérivés d'acide hydroxamique, leur utilisation en tant qu'inhibiteurs de LpxC et, plus spécifiquement, leur utilisation pour traiter des infections bactériennes.