HUMAN ANTI-SOD1 ANTIBODIES

Provided are novel human copper-zinc superoxide dismutase, also known as superoxide dismutase 1 or SOD1, specific antibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for SOD1 are also di...

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Bibliographische Detailangaben
Hauptverfasser: MONTRASIO, FABIO, NITSCH, ROGER, HOCK, CHRISTOPH, BARENCO MONTRASIO, MARIA GRAZIA, WELT, TOBIAS, MAIER, MARCEL, GRIMM, JAN, MCAFOOSE, JORDAN
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Provided are novel human copper-zinc superoxide dismutase, also known as superoxide dismutase 1 or SOD1, specific antibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for SOD1 are also disclosed. The antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for SOD1 targeted immunotherapy and diagnosis, respectively. L'invention concerne de nouveaux anticorps spécifiques de la superoxyde dismutase humaine à cuivre-zinc, aussi connue en tant que superoxyde dismutase 1 ou SOD1, ainsi que des fragments, des dérivés et des variants de ceux-ci ainsi que les procédés apparentés à ceux-ci. L'invention concerne aussi les essais, trousses et supports solides liés aux anticorps spécifiques pour la SOD1. L'anticorps, la(les) chaîne(s) d'immunoglobuline, ainsi que les fragments de liaison, dérivés et variants de ceux-ci peuvent être utilisés dans des compositions pharmaceutiques et diagnostiques pour l'immunothérapie et le diagnostic ciblés de la SOD1, respectivement.