APTAMERS TO 4-1BB AND THEIR USE IN TREATING DISEASES AND DISORDERS

The present disclosure relates generally to the field of nucleic acids and, more particularly, to aptamers capable of binding to 4-1BB; pharmaceutical compositions comprising such 4-1BB aptamers; and methods of making and using the same. La présente invention concerne d'une manière générale le...

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Bibliographische Detailangaben
Hauptverfasser:	RESNICOW, DANIEL I, WILCOX, SHERI K, VAUGHT, JONATHAN, SCHNEIDER, DANIEL J, WAUGH, SHEELA
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DERIVATIVES THEREOF ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS SUGARS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present disclosure relates generally to the field of nucleic acids and, more particularly, to aptamers capable of binding to 4-1BB; pharmaceutical compositions comprising such 4-1BB aptamers; and methods of making and using the same. La présente invention concerne d'une manière générale le domaine des acides nucléiques et, plus particulièrement, des aptamères pouvant se lier à 4-1BB. L'invention porte en outre sur des compositions pharmaceutiques comprenant ces aptamères 4-1BB et sur des procédés associés de réalisation et d'utilisation.