NUCLEOPHILIC CATALYSTS FOR OXIME LINKAGE

The invention relates to materials and methods of conjugating a water soluble polymer to an oxidized carbohydrate moiety of a therapeutic protein comprising contacting the oxidized carbohydrate moiety with an activated water soluble polymer under conditions that allow conjugation. More specifically,...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	IVENS, ANDREAS, SIEKMANN, JUERGEN, HAIDER, STEFAN, ZOECHLING, OLIVER, TURECEK, PETER, ROTTENSTEINER, HANSPETER
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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