ARYLCYCLOPROPYLAMINE BASED DEMETHYLASE INHIBITORS OF LSD1 AND THEIR MEDICAL USE

The invention relates to (hetero)aryl cyclopropylamine compounds, including particularly the compounds of formula (I) as described and defined herein, and their use in therapy, including, e.g., in the treatment or prevention of cancer, a neurological disease or condition, or a viral infection. Thus,...

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Bibliographische Detailangaben
Hauptverfasser:	FYFE, MATTHEW COLIN THOR, ORTEGA MUNOZ, ALBERTO, ESTIARTE-MARTINEZ, MARIA DE LOS ANGELES, MARTINELL PEDEMONTE, MARC, TIRAPU FERNANDEZ DE LA CUESTA, INIGO
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The invention relates to (hetero)aryl cyclopropylamine compounds, including particularly the compounds of formula (I) as described and defined herein, and their use in therapy, including, e.g., in the treatment or prevention of cancer, a neurological disease or condition, or a viral infection. Thus, in one specific aspect the invention relates to formulas (II), (III), (IV), (V), (VI), (VII), (VIII), (IX). L'invention concerne des composés (hétéro)aryl cyclopropylamine, comprenant en particulier les composés de formule (I) tel que décrits et définis présentement, et leur utilisation en thérapie, comprenant par exemple, le traitement ou la prévention du cancer, d'une maladie ou d'un état neurologique ou d'une infection virale. Ainsi, dans un aspect spécifique, l'invention concerne les formules (II), (III), (IV), (V), (VI), (VII), (VIII), (IX).