ANTI-ANGIOGENIC COMPOSITION CONTAINING MACROLACTIN A AND A DERIVATIVE THEREOF AS ACTIVE INGREDIENTS

The present invention relates to an anti-angiogenic composition containing macrolactin compounds such as macrolactin A, 7-O-malonyl macrolactin A, and 7-O-succinyl macrolactin A as active ingredients. The macrolactin compounds according to the present invention strongly suppress angiogenesis in in v...

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Bibliographische Detailangaben
Hauptverfasser: CHUNG, SUNG-UK, KIM, DONG-HEE, KIM, JUNG-AE, KANG, JAE-SEON, HWANG, SUNG-WOO, KANG, YOU-RA, JI, YOUNG-HOON, KANG, KYUNG-RAN
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention relates to an anti-angiogenic composition containing macrolactin compounds such as macrolactin A, 7-O-malonyl macrolactin A, and 7-O-succinyl macrolactin A as active ingredients. The macrolactin compounds according to the present invention strongly suppress angiogenesis in in vivo experiments, and can be used as a pharmaceutical composition for preventing or treating diseases caused by angiogenesis.