COMPOUNDS TO BE USED IN THE TREATMENT OF DISEASES BASED ON THE EXPRESSION OF TOXIC TRANSCRIPTS

The invention relates to compounds for use in the treatment of diseases based on the expression of toxic transcripts. The invention relates to peptide molecules, specifically hexapeptides, for the prevention and/or treatment of diseases having an etiology based on the presence of toxic transcripts c...

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Bibliographische Detailangaben
Hauptverfasser:	ARTERO ALLEPUZ, RUBEN DARIO, ORZAEZ CALATAYUD, MARIA DEL MAR, LLAMUSI TROISI, MARIA BEATRIZ, GARCIA LOPEZ, AMPARO, PEREZ PAYA, ENRIQUE, PEREZ ALONSO, MANUEL
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to compounds for use in the treatment of diseases based on the expression of toxic transcripts. The invention relates to peptide molecules, specifically hexapeptides, for the prevention and/or treatment of diseases having an etiology based on the presence of toxic transcripts comprising repeating units CUG, CCUG, CGG, CAG and AAG, preferably: DM1 SCA8, DM2, FXTAS, HD and FA. L'invention concerne des composés utilisables dans le traitement de maladies fondées sur l'expression de transcrits toxiques. La présente invention concerne des molécules peptidiques, plus particulièrement, des hexapeptides pour prévenir et/ou traiter des maladies dont l'étiologie est fondée sur la présence de transcrits toxiques comprenant des unités récurrentes CUG, CCUG, CGG, CAG et AAG, de préférence: DM SCA8, DM2, FXTAS, HD et FA.