ANTIFUNGAL 5,6-DIHYDRO-4-[(DIFLUOROETHYL)PHENYL]-4H-PYRROLO[1,2-A][1,4]BENZODIAZEPINE AND 4-(DIFLUOROETHYL)PHENYL-6H-PYRROLO[1,2-A][1,4]BENZODIAZEPINE DERIVATIVES

The present invention concerns novel compounds of Formula (I) wherein R1, R2, R3, R4, R5 and R6 have the meaning defined in the claims. The compounds according to the present invention are active mainly against dermatophytes and systemic fungal infections. The invention further relates to processes...

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Bibliographische Detailangaben
Hauptverfasser: MAES, LOUIS JULES ROGER MARIE, DE WIT, KELLY, MEERPOEL, LIEVEN
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention concerns novel compounds of Formula (I) wherein R1, R2, R3, R4, R5 and R6 have the meaning defined in the claims. The compounds according to the present invention are active mainly against dermatophytes and systemic fungal infections. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament. La présente invention concerne de nouveaux composés de formule (I), dans laquelle R1, R2, R3, R4, R5 et R6 ont la signification définie dans les revendications. Les composés selon la présente invention sont actifs principalement contre les dermatophytes et les infections fongiques systémiques. L'invention concerne en outre des procédés de préparation de ces nouveaux composés, des compositions pharmaceutiques comprenant lesdits composés en tant qu'ingrédients actifs ainsi que l'utilisation desdits composés en tant que médicament.