PROCESS AND INTERMEDIATES FOR PREPARING LAPATINIB

The present invention provides a process for making lapatinib and its pharmaceutically acceptable salt by use of new intermediates. A new process for obtaining a pharmaceutical form of lapatinib ditosylate monohydrate is also provided. L'invention concerne un procédé de préparation du lapatinib...

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Bibliographische Detailangaben
Hauptverfasser:	CHU, GUODONG, ZHANG, XIAOHENG, CHEN, YUNG-FA, HENSCHKE, JULIAN PAUL, LIU, YUANLIAN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The present invention provides a process for making lapatinib and its pharmaceutically acceptable salt by use of new intermediates. A new process for obtaining a pharmaceutical form of lapatinib ditosylate monohydrate is also provided. L'invention concerne un procédé de préparation du lapatinib et de son sel pharmaceutiquement acceptable à l'aide de nouveaux intermédiaires et un procédé pour l'obtention d'une forme pharmaceutique du monohydrate de ditosylate de lapatinib.