METHOD FOR TREATING HEART FAILURE WITH STRESSCOPIN-LIKE PEPTIDES

The present invention relates to novel methods of treating heart failure comprising administering an amount of stresscopin-like peptide to a subject in need thereof; and substantially maintaining the amount of said peptide present in the plasma of said subject at a concentration resulting in a thera...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SHANKLEY, NIGEL P, GENGO, PETER J, SABBAH, HANI N
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention relates to novel methods of treating heart failure comprising administering an amount of stresscopin-like peptide to a subject in need thereof; and substantially maintaining the amount of said peptide present in the plasma of said subject at a concentration resulting in a therapeutic benefit without a substantial increase in the heart rate of said subject. The method involves the use of stresscopin-like peptides that are selective corticotrophin releasing hormone receptor type 2 (CRHR2) agonists.